Pharmaceutical development with commercialization of generic drugs with poor soluble substance – tablets of drug nimodipine
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15 صفحه اولSolid Sirolimus Self-microemulsifying Drug Delivery System: Development and Evaluation of Tablets with Sustained Release Property
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متن کاملSolid Sirolimus Self-microemulsifying Drug Delivery System: Development and Evaluation of Tablets with Sustained Release Property
The clinical application of sirolimus (SRL) as an immunosuppressive agent is largely hampered by its narrow therapeutic range. This study focused on developing SRL tablets with a sustained release profile for better safety. SRL was highly water insoluble and its solubility has been efficiently enhanced by preparing self-microemulsifying drug delivery system (SMEDDS). The SRL-SMEDDS was physical...
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ژورنال
عنوان ژورنال: Farmatsevtychnyi zhurnal
سال: 2018
ISSN: 0367-3057
DOI: 10.32352/0367-3057.3-4.17.07